Many diseases and health complications are believed to be linked to fat consumption, including obesity, diabetes, heart problems, and cancer. However, fats also play crucial roles in our bodies, such as aiding in the transport and absorption of fat-soluble vitamins A, D, E, and K. Fats also act as insulators for vital organs and as shock absorbers. With these functions in mind, it begs the question: Is fat truly the culprit behind various diseases? (1,2,3).

 
History of Dietary Fat Recommendations (4)
 

The confusion surrounding dietary fat intake has its roots in the past, as nutrition scientists struggled to effectively communicate their findings from nutrition studies to the public. Previously, the classic diet-heart hypothesis vilified dietary fat due to two key observations from observational studies and randomized controlled trials.

1. Controlled feeding trials showed that dietary saturated fatty acids and cholesterol elevated levels of serum total cholesterol and low-density lipoprotein (LDL) cholesterol (considered "bad" cholesterol).
2. Dietary fat intake was associated with increased levels of serum total cholesterol and LDL cholesterol, which were predicted factors for cardiovascular disease.
    

Current Insights on Dietary Fat Intake (4)

Past research focused heavily on singular causal outcomes, but contemporary extensive research has illuminated multiple pathways contributing to the development of cardiovascular diseases. These pathways include factors beyond total cholesterol intake or LDL levels, such as smoking, obesity, diabetes mellitus, hypertension, and more.

As a result, recommendations for dietary fat intake among individuals with cardiovascular disease and those seeking to prevent it need to evolve accordingly.
 

Types of Fats and Cholesterol, Along with Dietary Recommendations (4,5,6)
 

To comprehend dietary recommendations for fat and cholesterol intake, let's first explore the different types. Saturated fat, often labeled as "bad" fat, is solid at room temperature. It can contribute to weight gain and increased levels of LDL cholesterol in the bloodstream. Sources high in saturated fat include meat, chicken skin, margarine, and fatty dairy products.

Unsaturated fats, considered "good" fats, are divided into monounsaturated and polyunsaturated fats. They can elevate HDL (good cholesterol), lower LDL (bad cholesterol), reduce blood pressure, and decrease the risk of cardiovascular diseases. Examples of monounsaturated fats are palm oil, canola oil, olive oil, and cashew nuts. Polyunsaturated fats include corn oil, sunflower oil, and fish oil. For optimal results, studies suggest a 1:1 ratio blend of these two types of oils in cooking, such as combining palm oil and sunflower oil.

Trans fat, the least desirable type, forms during hydrogenation when liquid fats turn solid. Trans fat, or trans-fatty acids, are commonly found in processed and frozen foods to prolong shelf life. Consumption of trans fat should be limited, as it's associated with elevated LDL cholesterol levels, increased cardiovascular disease risk, and certain cancers. Sources of trans fat include margarine, fried foods cooked in unsaturated fats like sunflower oil, as well as ready-to-eat and canned foods.
 

In Conclusion (4,5)

While there isn't a specific universal standard for each fat type due to various factors, the World Health Organization (WHO) generally recommends fat intake between 20% to 30% of total calories. In Malaysia, this translates to about 45g to 67g of fat, roughly 3 to 5 tablespoons of oil (based on a 2000 kcal/day diet).

As consumers, it's vital to distinguish health-promoting fats from detrimental ones and limit the intake of harmful fats to cultivate a healthy eating lifestyle.

Practical steps include choosing fresh poultry or seafood over processed foods like tempura or finger foods. Cooking methods matter greatly; opt for steaming, baking, boiling, and grilling. When dining out, consider that many eateries reuse cooking oil, making healthier choices paramount.

Limiting trans-fat intake is crucial. Apart from processed and frozen foods, restrict consumption of high-cholesterol items such as mayonnaise, animal organs, and fish heads.

Being mindful of what you fuel your body with is as important as feeding your mind with positive thoughts. Nourish both body and mind with beneficial nutrients by selecting healthy fats. 

Calcium is among very common micronutrient heard by public and milk advertisement is the contributor to this. Through this many people know that calcium is very important for bone and teeth. Calcium can be found in various food products nowadays not only milk. It has becoming partly marketing strategy for food company to incorporate calcium in their food product especially if the target consumer is children or elderly since many people know that calcium is vital for these two groups, children, and elderly.

Function of Calcium?

Body needs calcium for strong bones and teeth. Calcium is also required to carry out important function such as for muscle to move, for nerves system to carry messages between brain and body parts, for blood vessels to move blood throughout the body, and for body to help release hormones and enzyme that affect almost every function in the human body (1,2,3).

How much calcium is needed?

Normal adult need about 1000 mg of calcium daily, however there are certain condition which require to consume up to 1300 mg of calcium daily such as for pregnant lady, lactating mother, post-menopausal women, and man who is above 70 years old of age (1,2,4).

Calcium and diet

Body does not produce calcium, so it needs to be consumed from foods. Luckily, calcium can be found in variety of foods such as dairy products, dark leafy vegetables, fish, and many other fortified food products (1,2,3).   As for our local food products sardine, anchovies, cencaluk, budu, tofu, tempeh, broccoli, kalian, and tapioca leaves are among food that is high with calcium (4).

It is also important to take note that in order to absorb calcium, body needs vitamin D. Only a few foods containing small amount of natural vitamin D, such as egg yolks and salmon with bones. Mostly, we rely on the exposure to sunlight in order to get enough vitamin D, of course in Malaysia the country with sun all year long have no problem with this! However, as currently we are still in the so to say the ‘lockdown’ phase thus it is very important to remind everyone to get the sunlight every day at least 20 minutes for its vitamin D and calcium absorption (1,2,4).

Though all the foods stated above are easily found, but there are conditions which hinder individuals from getting enough calcium from diet thus require it from calcium supplementation.

Condition for calcium supplementation

Before considering calcium supplement, individuals must understand how much calcium needs by the body (stated above). Then individuals must seek help from nutritionist, dietitian, pharmacist, or doctors, where they will assess your calcium consumption from your diet through diet recall. If the calcium intake falls short thus you need to top up calcium from supplement.

Hypertensive individuals and diet with large amounts of sodium.

Several literature reviews on topic of total calcium intake from food and supplements with regards to hypertension suggested that there is possible link to lowering high blood pressure. However, since most of the study design have small number of subjects, and were tested with people from different background, and not to mention possess various kind of biases thus making it difficult for scientist to draw conclusion (1,2).

However, a large study subject (Women’s Health Study), found out that calcium intake was inversely associated with risk of hypertension in middle-aged and older women, in terms of preventing hypertension (1,2).

The consumption of high sodium food lead to more calcium excretion through the urine, which will lead to constriction of blood vessels, which in the end resulting  in high blood pressure. Drinking large water after consuming salty food, is not enough, as it may be making blood pressure return to its slightly normal condition, but it is not helping with the loss of calcium (1,2,5).

Pregnant and lactating mother

Often times, pregnant women is being reminded of how important is folic acid for the baby, even from the trying to conceive period, healthcare providers already advise them to consume folic acid, in order to prevent spina bifida to the baby. However, calcium is as well very important for mothers throughout pregnancy and lactating period especially for mother who is lack of calcium from diet (1).

Several professional organizations recommend calcium supplements during pregnancy for women with low calcium intakes to reduce the risk of preeclampsia (a condition where gestational hypertension always occur). For example, the American College of Obstetrics and Gynaecology (ACOG) states that daily supplementation with 1,500–2,000 mg calcium may reduce the severity of preeclampsia in pregnant women who have calcium intakes less than 600 mg/day. Similarly, the World Health Organization (WHO) recommends 1,500–2,000 mg calcium for pregnant women with low dietary calcium intakes, particularly those at higher risk of gestational hypertension (1).

As for normal healthy mother, the consumption of calcium is especially important during lactating period, mother may notice symptoms such as cramps which indicates lack of calcium during pregnancy and lactation period. Also if a mother is on iron supplementation as well, it is advisable to not consume both at the same time, it is best to gap several prior the consumption of these two since it can interfere with the absorption (1,2).

Individuals with lactose intolerance and limit dairy products

Individuals with lactose intolerance usually, is unable to consume food that has high amount of calcium especially if it come from milk and dairy source of food. Thus, lactose intolerance individuals need to consume it form dark leafy vegetables and soy-based product. However, in most cases the consumption is not enough or individuals with lactose intolerance consume not enough vegetable rich with calcium or other food source rich with calcium, thus for this specific population calcium supplementation is needed either from fortified food product such as ready to eat cereals or from calcium supplementation tablet itself.

Individuals receiving treatment on certain medication in the long period

Well, there are certain medication which can influence the absorption of calcium. Medication such as to treat osteoporosis (bisphosphonates), antibiotics (fluroquinolone), medication to treat low thyroid problem (levothyroxine), anticonvulsant (phenytoin), diuretic medication (Lasix and bumex), antacids containing aluminium and magnesium and also glucocorticoids (prednisone). These are all either causing calcium loss in the urine or cause calcium depletion in the bone. Thus, if you are on these medication, it is advisable to take calcium rich foods four hours prior or after the intake of medication, so that it would not interfere with the absorption of calcium, it is also best if you consume calcium supplementation if you do have poor intake of calcium rich food as well (2). 

In conclusion, in these situations, calcium supplements may help you meet your calcium requirements. Talk with your doctor or dietitian about whether calcium supplements are right for you.

References

1. National Institute of Health (NIH). Department of Health and Human Service. Calcium. Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/ (Accessed on November 18, 2020).
2. National Institute of Health (NIH). Department of Health and Human Service. Calcium. Fact Sheet for Consumers. https://ods.od.nih.gov/factsheets/Calcium-Consumer/ (Accessed on November 18, 2020).
3. Mayo Clinic. Nutrition and Healthy Eating. Healthy Lifestyle. Calcium and calcium supplements: Achieving the right balance. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/calcium-supplements/art-20047097 (Accessed on November 18, 2020).
4. Ministry of Health (MOH). National Coordinating Committee on Food and Nutrition. Recommended Nutrient Intake (RNI): A Report of the Technical Working Group on Nutritional Guidelines (2017).
5. Harvard T.H. Chan. School of Public Health. The Nutrition Source. Calcium. https://www.hsph.harvard.edu/nutritionsource/calcium/ (Accessed on November 18, 2020).

Grape seed extract (GSE) is derived naturally from grape seed and is commonly used in dietary supplements for a variety of purposes. It is created by removing, drying, and pulverising the bitter tasting grape seeds. It contains a lot of antioxidants like phenolic acids, anthocyanins, flavonoids, and oligomeric proanthocyanidins complexes (OPC). Grape seed extract, in fact, is regarded as one of the best sources of proanthocyanidins. As a result, grape seed extract provides numerous benefits to the human body, including disease prevention, protection against oxidative stress, tissue damage, inflammation, and many more. In this article, we will look in depth at the potential health benefits of grape seed extract (GSE) based on studies:

Wound healing activity and antioxidant properties. 

Numerous studies have shown that grape seed extract contains a high level of antioxidants. Using punctured wounded mice, researchers discovered that mice treated with GSE in the wound affected area grew tissue faster than mice treated with only normal saline. Another difference between GSE-treated mice and placebo-treated mice was more organized tissue formation and a higher rate of collagen deposition.

Topical application of 2% GSE cream in the area of a post-surgery surgical wound heals the wound completely in an average of 8 days, compared to 14 days for placebo. This is due to GSE's vascular endothelial growth factor (VEGF) properties, which promote the regeneration of damaged blood vessels while increasing the amount of free radicals present at the wound site. Free radicals aid in the killing and removal of pathogenic bacteria and endotoxin from the site, as well as in the healing of wounds

Apart from wound healing and skin health properties, it also has anti-ageing properties. GSE proanthocyanidins delay skin ageing by reducing lipid oxidation on the skin structure.

Cardiovascular and antihypertensive properties. 

Cardiovascular disorders (CVD) are among the major problems that arise due to modern, unhealthy lifestyles, which are the primary cause of death worldwide. It is a disorder that affects the condition and function of the heart and blood vessels in general. Changes in these two can result in cardiac arrest, heart stroke, hypertension, chest pain, and other complications. Studies show that GSE may prevent atherosclerosis (a condition where there is a build-up of fats, cholesterol, etc. in the blood vessel walls, which can restrict blood flow), inhibit or limit the oxidation of LDL (bad cholesterol), reduce inflammation, inhibit platelet aggregation, and lower blood pressure. It lowers blood pressure by suppressing oxidative stress and inhibiting the angiotensin-converting enzyme (ACE) and nitric oxide, which mediate vasodilation, hence making the constricted blood vessels dilate and improving blood pressure.

Antimicrobial activity 

GSE has been shown to have antimicrobial properties; for example, when applied topically, resveratrol in GSE increases the production of cathelicidin, which inhibits the growth of Staphylococcus aureus. In another study, quercetin, caffeic acid, and quercetin-3-0-rutinoside in GSE were responsible for the inhibition of Listeria monocytogenes. It is also worth noting that GSE had the highest inhibition activity against almost all Listeria species. The review on the benefits of GSE also reported that the antimicrobial effect of GSE is attributed to changes in cell morphology and DNA content. 

Cosmetic and nutraceuticals

Skin ageing is a natural process which occurs due to the external and internal factors involving genetic, hormonal, and environmental factors. GSE is rich in proanthocyanidin help to reduces the lipid oxidation of cellular structure of the skin and inhibit the production of free radicals. A study was carried out in which the anti-ageing effect of GSE was investigate. The study concluded that GSE has a promising role as an anti-ageing compound.

GSE help skin structure by strengthening the collagen-based tissue (by increasing the collagen cross links). It also increases the synthesis of collagen and the conversion of collagen from soluble into insoluble one.

In conclusions,

GSE has various benefits to health due to its high antioxidant properties, it is able to scavenge the free radicals which an essential feature that could help with various body functions.

 References

1. National Institute of Health (NIH). National Centre for Complementary and Integrative Health (NICCH). Grape Seed Extract. https://www.nccih.nih.gov/health/grape-seed-extract (Accessed on March 15, 2021)
2. 10 Benefits of Grape Seed Extract, Based on Science. https://www.healthline.com/nutrition/grape-seed-extract-benefits (Accessed on March 15, 2021).
3. Gupta, M., Dey, S., Marbaniang, D., Pal, P., Ray, S., & Mazumder, B. (2020). Grape seed extract: Having a potential health benefit. Journal of food science and technology, 57(4), 1205-1215

The infographic above explains the types of good and bad fats. But what about the differences between Omega 3, 6, and 9? All these three fats can be considered good fats, but there are certain things that distinguish them from one another.

MUFA or Omega 9

Monounsaturated fatty acid (MUFA), also known as omega 9, is named because of the double bond position, which is on the ninth position from the omega end. It is a type of fat that is found in vegetable and animal fats such as canola oil, sunflower oil, olive oil, and nuts. Unlike polyunsaturated fatty acids (PUFA), omega-9 is a non-essential fat, which means the body is able to produce these types of fat. However, there are also benefits when it is obtained from food, such as reducing the risk of cardiovascular disease and stroke, reducing LDL cholesterol (bad cholesterol), increasing HDL cholesterol (good cholesterol), and helping to eliminate plaque buildup in the arteries, which can cause heart attacks and strokes.

PUFA or Omega 3 & Omega 6 

Polyunsaturated fatty acids (PUFA) can be divided into Omega 3 and Omega 6. The difference between these two is that the position of the double bond for Omega 3 is in the third position from the end, whereas for Omega 6, it is in the sixth position from the end.

Among the types of Omega 3 with extensive scientific research are eicosapentanoic acid (EPA), docosahexaenoic acid (DHA), and alpha-lipoic acid (ALA). The difference between these three types of Omega-3 fats is the number of carbon atoms: 18, 20, and 22 for ALA, EPA, and DHA, respectively. ALA can be converted to EPA and then to DHA, but the conversion, which usually occurs in the liver, is less than 15%, which is why it is recommended to consume EPA and DHA directly from foods or dietary supplements. ALA is present in plant oils such as flaxseed, soybean, and canola oils. DHA and EPA are present in fish, fish oils, and krill oils. But the DHA and EPA in krill oil do not originate from krill but rather from the ingestion of microalgae.

Whilst, among the types of Omega 6 are linolenic acid (LA) and arachidonic acid (AA), The difference between these two is the position of the double bond in the omega-6 fatty acid chain. Linolenic acid (LA) is the same as ALA; it is an essential fatty acid that cannot be produced by the human body. Sources of food with LA are soybean oil, corn oil, safflower oil, peanut oil, cottonseed oil, and rice bran oil. While the sources of food for AA are peanut oil, meat, eggs, and dairy products,

Omega 3 and Omega 6 are beneficial for cardiovascular diseases because they can help manage cholesterol levels, triglycerides levels, and blood pressure levels. There is also certain supporting data that states that it can help with reducing weight and waist size, improving infant brain development in the foetus, and fighting inflammation. However, other than for cardiovascular health, the finding is quite inconclusive. But as for Omega 3 and 6 (PUFA) and heart health, the American Heart Association (AHA) recommends that 8–10% of calories should come from PUFA, as there is evidence that eating more PUFA—up to 15% of daily calories—in place of saturated fat can lower the risk of heart disease.

The diagram below shows the comparison between these three types of good fat: 

All in all, Omega 3, 6, and 9 are beneficial for cardiovascular health, as they can help with lowering LDL levels (bad cholesterol), increasing HDL levels (good cholesterol), and helping with blood pressure levels. Several other studies also mentioned that certain good fats can help with inflammatory diseases such as joint pain and skin diseases such as eczema. However, consumption of all these fats must be in balance since overconsumption of them can have serious health effects! However, replacing bad fat (or even good fat) with refined carbohydrates does not help your health either. It is so important to note that everything must be in balance, and consuming healthy food is not about one type of food only; it is about variety, quality, and the food source as well!

References
 

1. Ministry of Health Malaysia (MOH). Hyperlipidemia.

2. Harvard T.H Chan. School of Public Health. Types of fat. https://www.hsph.harvard.edu/nutritionsource/what-should-you-eat/fats-and-cholesterol/types-of-fat/

3. Harvard T. H Chan. School of Public Health. Saturated fat or not does type of fat matter.  https://www.hsph.harvard.edu/nutritionsource/2014/05/15/saturated-or-not-does-type-of-fat-matter/

4. Healthline. Omega 3, 6, and 9. https://www.healthline.com/nutrition/omega-3-6-9-overview#omega-6

Consumption of fish is important as it is a good source of protein. It is recommended to consume one fish per day, according to the Malaysian food pyramid. This is because the consumption of fish in Malaysia is rarely equated with a risk of contamination with mercury, etc., unlike in western countries. This might be due to the types of fish and sizes of fish that we are consuming here as compared to other parts of the world. It is said that the bigger the fish, the more contamination it has; hence, there is a recommendation for pregnant mothers to consume small fish rather than big fish to avoid the risk of contamination.

Research on the benefits of fish oil supplementation also varies greatly, which is why in this article we are going to list out who might need a fish oil supplementation in their daily lives!

The benefits of ingesting fish oil can differ significantly between studies. A study found a connection between these omega-3 fatty acids and mental health disorders and that EPA and DHA can speed up brain development even in young children. Additionally, studies have demonstrated that it can help treat cardiovascular diseases, joint pain, and eczema. The question is, is it true that all of these effects can be obtained from fish oil consumption? (1)

Individual with mental health problems/disorders

In three lengthy studies spanning the years 1988 to 2008, researchers looked at the relationship between fatty acid intake and suicide risk among more than 205 000 participants. They discovered no proof that eating fish or fatty acids reduced the risk of suicide. "The vast majority of earlier research on whether fatty acid intake has any positive effects on mental health has been based on results from depression screening. The only time this relationship has been studied with concrete data on suicide mortality is in our study, which is also the largest of its kind.” (2)

While a study found that eating a balanced diet and exercising regularly are better for brain health than taking fish oil or omega-3 fatty acid supplements, A study of 3073 elderly people at risk of macular degeneration, an age-related cause of vision loss, found little benefit from omega-3 supplements on memory. Omega 3 supplements or a placebo were given to study participants at random for a five-year period.  According to the researcher, a healthy diet cannot be replaced by a supplement; therefore, if you eat a healthy diet rich in fruits, vegetables, and marine fish, you probably don't need to take a fish oil supplement. According to this study, the overall dietary pattern is more important than a single nutrient (2).

Individuals with cardiovascular disease

Recently, there have been many studies suggesting that Omega 3 will not lower the risk of heart problems. To answer this, Dariush Mozaffarian, cardiologist from Harvard Medical School, said that he gathered 20 previous studies involving more than 68, 000 patients since 1989 and found that, overall, fish oil supplements did neither harm nor good since they did not significantly reduce people’s risk of mortality, cardiac death, heart attack, or stroke. But according to him, the research link between fish oil supplementation and heart problems is rather complex since it does not only take fish oil to shield the heart from various problems and diseases; it also takes weight status, exercise frequency, cigarette or substance use, and many more (3,4,5).

Which is why, interpreting the study, we would still recommend customers and patients consume more fish as a first-line measure. But if you do not like fish, or you feel like your consumption of fish is not enough, or you simply want to be sure that your body is getting omega 3, there is no harm in taking fish oil; it will certainly help with the essential nutrient, since omega 3 is a nutrient that your body cannot produce and can only get from diet (3,4,5).

Individuals with skin problem

A systematic review for the treatment of atopic dermatitis or eczema using fish oil supplementation is very scarce; the studies available are all small-sample studies. Not only are these three studies small, but they are also described as poor methodological studies by the reviewer, as they have many confounding factors. However, the outcomes of these studies show positive outcomes for eczema and overall daily living as compared to placebo (6, 7).

Another convincing relationship between consumption of fish oil and skin health is that in a study where pregnant women were given fish oil during pregnancy and followed up for 6 years, it was found that consumption of fish oil during pregnancy led to a positive skin health outcome for babies skin. The study also concluded that maternal supplementation with fish oil might have prophylactic potential for long-term prevention of asthma in offspring (6, 7).

In conclusion, consumption of fish oil has mixed results in studies depending on what kind of problem we are looking to solve with fish oil. Since there are various factors influencing a particular health problem, There is no magic pill in this world, honey! You need to, however, eat healthily, consume a lot of vegetables and fruits, and exercise, but if you think that you do not get enough omega 3 from your diet because you dislike fish, are afraid to consume fish regularly due to contamination, etc., or simply would like to make sure that your body has enough omega 3, then there is no harm in taking fish oil supplementation. It's just that in order to make sure you get the right omega 3 for your body, buy it from a pharmacy, make sure the product has a Ministry of Health (MOH) notification number, and simply ask a healthcare professional which omega 3 supplementation suits you, simply for the dosage and perhaps current medication that you are on, and you are good to go!

References

1. Harvard T.H Chan. School of Public Health. Fish: Friend or Foe? https://www.hsph.harvard.edu/nutritionsource/fish/

2. Harvard T.H. Chan. School of Public Health. No mental health benefit from fish oil. https://www.hsph.harvard.edu/news/hsph-in-the-news/no-mental-health-benefit-from-fish-oil/\

3. Harvard T.H. Chan. School of Public Health. https://www.hsph.harvard.edu/news/hsph-in-the-news/fish-stroke-risk-mozaffarian/

4. Harvard T.H Chan. School of Public Health. Major Meta Analysis in Clinical Trial Omega 3 Supplemeny link with lower risk of CVD.  https://www.hsph.harvard.edu/news/press-releases/in-major-meta-analysis-of-clinical-trials-omega-3-fish-oil-supplements-linked-with-lower-cardiovascular-disease-risk/

5. Harvard T.H. Chan. School of Public Health. Fish Oil Supplementation and Heart Health. https://www.hsph.harvard.edu/news/hsph-in-the-news/mozaffarian-fish-oil-supplements-heart-health/

6. Schlichte, M. J., Vandersall, A., & Katta, R. (2016). Diet and eczema: a review of dietary supplements for the treatment of atopic dermatitis. Dermatology practical & conceptual, 6(3), 23–29. https://doi.org/10.5826/dpc.0603a06

7. Huang, T. H., Wang, P. W., Yang, S. C., Chou, W. L., & Fang, J. Y. (2018). Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin. Marine drugs, 16(8), 256. https://doi.org/10.3390/md16080256

Why do we need CoQ10?

CoQ10's main function is to act as an energy transfer molecule, where it is a co-factor in the production of energy. Essentially, all cellular functions are dependent on an adequate supply of energy, which explains why coq10 is vital for all tissues and organs. CoQ10 is also one of the most significant lipid antioxidants that prevents the generation of harmful substances in the body, such as free radicals, which can lead to the modification of proteins, lipids, and DNA.

Antioxidant is defined as a substance that inhibits the oxidation process or is a scavenger of free radicals that are produced by normal body processes, hence making the body more stable.

Due to its function as antioxidants, not only can it help neutralize free radicals and prevent the damage caused by free radicals, but it can also improve energy and augment the immune system.

Who needs CoQ10?

There are certain individuals who need to consume more CoQ10 as the amount in their bodies is diminishing.

1. Individual who is consuming or on statin medication (medicine used to lower high blood levels of cholesterol or triglycerides to prevent heart problems). This is because studies show that statins interfere with the production of mevalonic acid, which is used to form CoQ10. Thus, individuals who consume statins have low levels of CoQ10 in their bodies.
2. Individuals with heart conditions, such as heart failure and angina, may benefit from taking a CoQ10 supplement. A review of 13 studies in people with heart failure found that 100 mg of CoQ10 per day for 12 weeks improved blood flow from the heart.
3. As CoQ10 is involved in the production of energy, it can be used by athletes and those who would like to boost physical performance. A 6-week study in 100 German athletes found that those who supplemented with CoQ10 daily experienced significant improvements in physical performance, measured as power output, compared to a placebo group. CoQ10 supplements help reduce the inflammation associated with heavy exercise and may even speed recovery.

How much do we need CoQ10? 

A typical CoQ10 dosage is about 30–90 mg per day, taken in divided doses, but the recommended amount can be as high as 200 mg per day. CoQ10 is a fat-soluble antioxidant, so it is better absorbed when taken with a meal that contains oil or fat. The clinical effect of CoQ10 may take up to eight weeks.

Food source with CoQ10?

Primary dietary sources of CoQ10 include oily fish (such as salmon and tuna), organ meats (such as liver), and whole grains. Most individuals obtain sufficient amounts of CoQ10 through a balanced diet, but supplementation may be useful for individuals with particular health conditions. CoQ10 is available as a supplement in several forms, including soft gel capsules, oral spray, hard shell capsules, and tablets.

Safety precautions

Consumption of CoQ10 might not really be suitable for individuals who consume warfarin medication, pregnant women, or breastfeeding mothers. 

References

1. Saini R. (2011). Coenzyme Q10: The essential nutrient. Journal of pharmacy & bioallied sciences, 3(3), 466–467. https://doi.org/10.4103/0975-7406.84471
2. National Institute Health (NIH). National Centre for Complementary and Integrative Health. Coenzyme Q10. https://www.nccih.nih.gov/health/coenzyme-q10
3. CoQ10 dosage: How much you should consume per day? https://www.healthline.com/nutrition/coq10-dosage

Therapeutic benefit in hypertension.

Hypertension, also known as high blood pressure, is a condition in which the blood pressure rises above 120/80. CoQ10 has been shown in animal model studies to significantly reduce blood pressure levels while having no effect on other hypertension-related parameters such as plasma renin, serum/urine sodium and potassium, or urinary aldosterone. It is also suggested that varying COQ10 dosage results in a reduced need for medication. In a human study, taking 60 mg of CoQ10 twice daily for 8 weeks reduced blood pressure, plasma inulin, glucose, and several lipid compounds. Other human studies have ranged from 100 to 225mg/day for 4.4 to 10 months.

Therapeutic benefit in coronary artery disease.

Coronary heart disease (CHD) occurs when the coronary arteries that supply oxygen-rich blood to your muscles become narrowed due to a gradual buildup of fatty material within their walls. The condition is also referred to as atherosclerosis. Pretreatment with CoQ10 has been shown in animal studies to reduce myocardial ischemia (occurs when blood flow to the heart muscle is obstructed by a partial or complete blockage of plaque buildup (atherosclerosis)) and cardiac dysfunction. In human studies, a dose of 300 mg/day for 7 days straight improves heart efficiency as measured by oxygen consumption per energy formed. Another study on humans using a 150mg dose of CoQ10 found that the supplement increased treadmill exercise tolerance. However, because these two studies involved a small number of subjects, they are not statistically significant.

Therapeutic benefit of congestive heart failure 

A small study of 17 patients with congestive heart failure discovered that using 30 mg/day of coenzyme Q10 improved the patients' condition, with 53% of the patients becoming asymptomatic after four weeks of treatment (no symptoms). Another large-scale study involving 2664 patients who took 50-100mg/day of coenzyme Q10 for three months found that 54% of patients improved in their symptoms of insomnia, nocturia, and vertigo. 

Is CoQ10 recommended for heart health prevention and treatment?

In conclusion, it appears that CoQ10 may be beneficial for heart health prevention and treatment, particularly for people with coronary heart disease, hypertension, and congestive heart failure. This is due to its ability to prevent LDL oxidation. It also appears that the majority of patients with heart disease are deficient in coenzyme Q10, which can lead to a variety of heart-related complications later on.

References

1. Sarter, B. (2002). Coenzyme Q10 and cardiovascular disease: a review. Journal of Cardiovascular Nursing, 16(4), 9-20.

Fiber is a type of carbohydrate that our body is unable to digest. Though most carbohydrates are broken down into sugar molecules, fiber cannot be broken down into sugar molecules, and instead it passes through the body undigested. Fiber helps regulate sugars in the body and helps keep hunger and blood sugar in check.

Children and adults need at least 20 to 30 grammes of fiber per day for good health. It can be obtained by consuming a diet rich in whole grains, vegetables, legumes, nuts, and fruits.

There are two types of fiber: soluble fiber and insoluble fibre.

• Soluble fiber is a type of fiber that dissolves in water and can help lower glucose levels and blood cholesterol levels. Foods with soluble fiber include oatmeal, nuts, beans, lentils, apples, and blueberries.

• Insoluble fiber is a type of fiber that does not dissolve in water. It can help food move through the digestive system, promoting regularity and helping to prevent constipation. Foods with insoluble fibers are wheat, whole wheat bread, whole grain couscous, brown rice, legumes, carrots, cucumbers, and tomatoes.

There are various studies confirming that consumption of a diet high in fiber helps to make the overall body function healthier.

Heart Health

In a Harvard study with over 40, 000 male health professionals, researchers found that consumption of a high-fiber diet reduced the risk of getting coronary heart disease by 40%. Another study conducted by Harvard among female nurses also found similar findings: a high-fiber diet lowers the risk of metabolic syndrome (a combination factor of heart disease and diabetes). These factors are high blood pressure, high insulin levels, excess weight, a high triglyceride level, and a low HDL level (good cholesterol level).

Diet suku – suku separuh adalah saranan diet oleh Kementerian Kesihatan Malaysia (KKM) untuk cara pemakanan sihat. Pelbagai langkah dan inisiatif telah dilakukan bagi mempromosikan amalan pemakanan sihat kepada rakyat Malaysia.

MegaLive menyambut baik saranan ini dengan turut sama mempromosikan amalan pemakanan sihat kepada semua.

Suku – suku separuh adalah diet yang merangkumi suku jumlah karbohidrat seperti nasi, mee, bihun, capati, roti dll, suku jumlah protein seperti ayam, ikan, sotong dll dan separuh jumlah sayur – sayuran dan buah – buahan. Pinggan yang dirujuk dalam saranan diet ini adalah pinggan berukuran 10 inci/ 25sm.

Contoh hidangan suku – suku separuh:

Eat Healthy Food

It is commonly assumed that the health of your eyes is unrelated to what you consume, but the truth is that it is. Consuming nutrient-dense foods will allow you to maintain good health, thereby avoiding complications that may arise in your eyes as a result of your health complications.

As part of a healthy diet, choose foods high in antioxidants, such as vitamins A and C, which have been shown to benefit eye health. Foods high in vitamins A and C include green leafy vegetables and foods with bright colours like orange and red. It also contains carotenoid, which is beneficial to the eyes. Carotenoid is an antioxidant found in plants that are brightly coloured, such as red, orange, yellow, and green. Aside from that, it can act as a cancer-fighting agent. Carotenoid works in the macular (the most sensitive part of the retina responsible for vision production and colour perception).

Lutein and zeaxhantin are types of carotenoids.

Inadequate antioxidant intake, alcohol consumption, or saturated fat consumption may result in free-radical reactions that harm the macula. High-fat diets can also cause deposits in the arteries that restrict blood flow. Because of the small size of the blood vessels that feed the eyes, they are especially sensitive to this.

Exercise regularly

By exercise regularly, body will have lower risk of getting various kind of metabolic disease such as diabetes, kidney problem and heart problem, thus lower the risk of getting complication that can impair eyes function. Example of metabolic disease that can impair eyes directly is, diabetes, which in the later stage can cause diabetic retinopathy. The condition where blood vessels of the light-sensitive tissue at the back of the eye (retina) is damaged. At first, it may cause no symptoms or mild blurry vision, eventually it can cause blindness.

Wear sunglasses

The American Academy of Opthalmology (AAO) encourages people to protect their eyes from the sun's harmful UV rays. Sunglasses are more than just a fashion statement; they are also a wise and healthy choice. Long-term sun exposure without adequate protection can increase the risk of eye disease such as cataract, macular degeneration, eye growth, and a rare form of eye cancer.

While short-term exposure can also damage the eyes. Sun reflecting off water can cause a painful sunburn on the front part of the eye, called photokeratitis. It causes redness, blurry vision, sensitivity to bright light, and in rare cases, even temporary vision loss.

The good news is that prevention is simple: Wear sunglasses that block 99 to 100 percent of both UVA and UVB radiation.

Quit smoking

Smoking is not only bad for your lungs. It can hurt your eyes, as well. Smoking increases your risk of eye diseases like macular degeneration and cataracts.

Eye care in conclusion

People usually take their eyesight and health for granted; it was only when we began to lose the ability that we began to take it seriously. Start taking care of your eyes now by doing the above. If you are constantly looking at a screen, you can also give your eyes a break every 20 minutes by looking 20 feet away for 20 seconds. If you have a family history of eye problems, schedule a comprehensive dilate eye exam on a regular basis. If you wear contact lenses, make sure to disinfect them and replace them on a regular basis. Also, remember to wash your hands before touching your eyes or face

References

• National Institute of Health (NIH). National Eye Institute (NEI) (July 2020). Keep your eyes healthy. https://www.nei.nih.gov/learn-about-eye-health/healthy-vision/keep-your-eyes-healthy (Accessed on July 28, 2020).
• Bausch + Lomb. Healthy Eyes. https://www.bausch.com/vision-and-age/20s-and-30s-eyes/healthy-eyes (Accessed on July 28, 2020)
• All About Vision. How carotenoid can keep your eyes healthy. https://www.allaboutvision.com/nutrition/carotenoids.htm#:~:text=According%20to%20nutrition%20research%2C%20an,macular%20degeneration%20later%20in%20life. (Accessed on July 28, 2020).
• Mayo Clinic. Diabetic Retinopathy. https://www.mayoclinic.org/diseases-conditions/diabetic-retinopathy/symptoms-causes/syc-20371611#:~:text=Diabetic%20retinopathy%20(die%2Duh%2D,or%20only%20mild%20vision%20problems. (Accessed on July 28, 2020)
• American Academy of Opthalmology. Sunglasses your prescription for eye health. https://www.aao.org/newsroom/news-releases/detail/sunglasses-your-prescription-eye-health (Accessed on July 28, 2020).

In this fast-changing world that we are in today, people want things to be done quick and always ready! People use various kind of devices and gadgets to speed up process of doing work. Initially, computer was built not for the sake of email and doing work, but it is actually to calculate and tabulate census for United States of America population since the population has grown bigger, it was started with a machine sort of punch card machine in 1880, where due to this the government save about $5 million in order to tabulate the census. From that sort of punch card machine, Alan Turing then presents another universal machine which capable of computing anything that is computable, the central concept of modern computer today is based on his ideas. Few years later, in 1939 Hewlet – Packard is founded by David Packard and Bill Hewlett in California, until today the computer that we are using is evolve from time to time, to the small smartphone on our hands that is capable of doing so many thing just like the bulky desktop (1).

All these technologies make us even more connected to devices like smartphone to connect with other people or to get things done. From paying bills, to designing, networking, sales, work, presentation, you name it all must be done using laptop, computer, smart phone, and the devices. The fact is everyone everyday is looking at the screen for long time, when the recommended hour to look at the screen is only 2 hours per day (2).

Why screening is bad for eyes?

White light that we see from sun and electronic devices is a combination from red, orange, yellow, green, blue, indigo, and violet light. Each of these lights has different energy and wavelength. Rays on red have longer wavelength and less energy, while the blue rays have shorter wavelength and more energy. Light that looks white can have a large blue component, which can expose the eye to a higher amount of wavelength from the blue end spectrum (3).

Sun also have this blue light, but blue light exposure from screen is small compared to exposure from sun, thus why makes it bad for eyes. Furthermore, screen exposure has closer proximity to eyes and the time spent looking at screen is longer than at the sun (3,4).

Almost all visible blue light penetrates the eyes through cornea, lens and reaches the retina, due to this, it makes eyes prematurely aging.

Blue light from computer screens and digital devices can decrease contrast leading to digital eyestrain. Fatigue, dry eyes, bad lighting, or how you sit in front of the computer can cause eyestrain. Symptoms of eyestrain include sore or irritated eyes and difficulty focusing. Apart from that, studies also suggested that continued exposure to blue light over time could lead to damaged retina cells. This condition can cause problems like age-related macular degeneration (4).

Macular degeneration is the result of photoreceptor cell death in the retina. The function of the photoreceptor cells is to capture visual images and signal them to the brain using a molecule called retinal. Retinal, which is produced by the eye, is triggered by blue light and causes various chemical reactions. These reactions within the eye can be poisonous to the photoreceptor cell molecules rendering them damaged. When these photoreceptor cells die, there’s no regeneration (4).

What can we do?

With the current work requirements where most of work and stuff need to be accomplished through the usage of electronic devices thus screening is very much essential, makes it even harder to take care eyes from the screen. No! There are actually ways to take care of your eyes still, apart from consume food that is high with antioxidants and vitamins that can improve eyesight condition you may also try and practice the tips below (5)!

The good news is that nutrition can prevent this from happening! A varied and balanced diet can help to prevent many diseases, including blindness. Many studies have found that consuming antioxidants, also known as cancer fighting agents, can help prevent vision loss. Antioxidants are compounds that aid in the scavenging of free radicals that can cause cell mutation and cancer.

Since many of these antioxidants are found in plant-based diets such as vegetables and fruits, one mechanism for this is said to be due to the prevention of other chronic diseases such as hypertension and diabetes, lowering the risk of vision loss. Lutein and zeaxanthin, vitamin A, omega 3, and vitamin C are all antioxidants that have been linked to vision health (2). 

Lutein and zeaxanthin are members of the carotenoid family, which is a well-known antioxidant for eye health. Apart from being found in green leafy vegetables like spinach, it can also be found in yellowish, orange-red plant-based foods like capsicum. In nature, lutein and zeaxanthin appear to absorb excess light energy to protect plants from overexposure to sunlight, particularly high-energy light rays known as blue light. While in the human body, lutein and zeaxanthin are abundant in the macula of the human eye, the name 'macula lutea' is derived from lutein, which means yellow spot.

The National Eyes Institute (NEI) conducted research on lutein, zeaxanthin, and the effect of carotenoids supplement taking in May 2013. It is the second largest eye- disease research study, namely, AREDS2. The purpose of this study was to see how nutrients, such as lutein and zeaxanthin, affected the prevention of AMD and other age-related eye diseases. For five years, participants in this study were given 10 mg of lutein and 2 mg of zeaxanthin every day. The use of daily antioxidant supplementation reduces the risk of progressive Age-related-Macular Degeneration (AMD) by 25% among those with early and intermediate macular degeneration, according to this study. However, it is unclear whether it can aid in the prevention of cataracts and their complications.

Vitamin A is another common antioxidant for the eyes. Night blindness is commonly caused by a lack of vitamin A. Vitamin A functions as photoreceptors, where it aids in the maintenance of light-sensing cells in the eyes. It's found in animal-based foods like dairy and egg yolk.

Omega 3 Fatty Acids (1,2)

EPA and DHA, which are derived from omega-3 fatty acids, are essential not only for brain development during infancy, but also for vision health. A study of people with dry eyes found that taking EPA and DHA supplements daily for three months significantly reduced dry eye symptoms by increasing tear fluid production (lacrimal fluid). Oily fish is a good source of EPA and DHA, and microalgae supplements are also available.

Vitamin E (1,3)

Vitamin E is a fat-soluble vitamin that protects fatty acids from oxidation. Because the retina contains a high concentration of fatty acids, adequate vitamin E intake is essential for good eye health. A study that supplemented 7 mg of vitamins E found that it can reduce the risk of age-related cataracts by 6%. However, a randomized controlled study discovered that vitamin E supplementation does not slow or prevent the progression of people who already have eye problems. Almonds, sunflower seeds, and flaxseed oil are good sources of vitamin E.

Vitamin C (1,3)

Vitamin C is commonly consumed for skin purposes, but since many studies have discovered that vitamin C is an important antioxidant for eye health as well, many supplements are now beginning to incorporate vitamin c rich sources in eye supplementation. It's a good thing because it gives you two effects in one!

Zinc (1,3)

Zinc is abundant in the eyes. It functions as a transporter for vitamin A, which is later involved in the formation of visual pigments in the retina known as melanin. As a result, zinc deficiency has been linked to night blindness. Oysters are a natural dietary resource high in zinc that is also beneficial to men's health!

In conclusion

Taking care of your vision health entails more than just avoiding screens and wearing sunglasses when you go outside. It is also what you put inside your body. Again, healthy eating is important for overall health, including vision!

References

• All About Vision. Lutein and Zeaxanthin. Eye and vision benefits. https://www.allaboutvision.com/nutrition/lutein.htm (Accessed on Aug, 26, 2020).American

• Optometric Association (AOA). Diet and Nutrition. Adding Powerful Antioxidants in your diet. https://www.aoa.org/healthy-eyes/caring-for-your-eyes/diet-and-nutrition?sso=y (Accessed on Aug, 26, 2020)

• 8 Nutrients that will optimize your eye health. https://www.healthline.com/nutrition/8-nutrients-for-eyes. (Accessed on Aug 26, 2020)